ロード中...

Mechanism of Action of T-705 Ribosyl Triphosphate against Influenza Virus RNA Polymerase

T-705 (favipiravir; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) selectively and strongly inhibits replication of the influenza virus in vitro and in vivo. T-705 has been shown to be converted to T-705-4-ribofuranosyl-5-triphosphate (T-705RTP) by intracellular enzymes and then functions as a nucleotide...

詳細記述

保存先:
書誌詳細
主要な著者: Sangawa, Hidehiro, Komeno, Takashi, Nishikawa, Hiroshi, Yoshida, Atsushi, Takahashi, Kazumi, Nomura, Nobuhiko, Furuta, Yousuke
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811313/
https://ncbi.nlm.nih.gov/pubmed/23917318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00649-13
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!