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Favipiravir (T-705), a novel viral RNA polymerase inhibitor

Favipiravir (T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) is an antiviral drug that selectively inhibits the RNA-dependent RNA polymerase of influenza virus. It is phosphoribosylated by cellular enzymes to its active form, favipiravir-ribofuranosyl-5′-triphosphate (RTP). Its antiviral effect is...

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Bibliografski detalji
Glavni autori: Furuta, Yousuke, Gowen, Brian B., Takahashi, Kazumi, Shiraki, Kimiyasu, Smee, Donald F., Barnard, Dale L.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880838/
https://ncbi.nlm.nih.gov/pubmed/24084488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.09.015
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