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Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase

Favipiravir (T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) is an anti-viral agent that selectively and potently inhibits the RNA-dependent RNA polymerase (RdRp) of RNA viruses. Favipiravir was discovered through screening chemical library for anti-viral activity against the influenza virus by Toy...

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Détails bibliographiques
Publié dans:Proc Jpn Acad Ser B Phys Biol Sci
Auteurs principaux: FURUTA, Yousuke, KOMENO, Takashi, NAKAMURA, Takaaki
Format: Artigo
Langue:Inglês
Publié: The Japan Academy 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713175/
https://ncbi.nlm.nih.gov/pubmed/28769016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.93.027
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