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Types of tolerance seen in autoreactive phosphocholine-specific B cells are dependent on the idiotype of the receptors expressed

Phosphocholine (PC) is the immunodominant epitope found on the surface of a number of microorganisms, including Streptococcus pneumoniae (SPn), and is thought to play a vital role in the pathogenesis of SPn. B cells expressing M167Hκ24L immunoglobulin receptors specific for PC have been shown to be...

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Detalhes bibliográficos
Main Authors: Mi, Qing-Sheng, Kenny, James J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811122/
https://ncbi.nlm.nih.gov/pubmed/23624878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2013.17
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