Partial tolerance of autoreactive B and T cells to erythrocyte-specific self-antigens in mice

BACKGROUND: Breakdown of humoral tolerance to RBC antigens may lead to autoimmune hemolytic anemia, a severe and sometimes fatal disease. The underlying mechanisms behind the breakdown of humoral tolerance to RBC antigens are poorly understood. DESIGN AND METHODS: In order to study the pathogenesis...

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Detalhes bibliográficos
Main Authors: Hudson, Krystalyn E., Hendrickson, Jeanne E., Cadwell, Chantel M., Iwakoshi, Neal N., Zimring, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590090/
https://ncbi.nlm.nih.gov/pubmed/22733018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.065144
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