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The Fas/CD95 Receptor Regulates the Death of Autoreactive B Cells and the Selection of Antigen-Specific B Cells

Cell death receptors have crucial roles in the regulation of immune responses. Here we review recent in vivo data confirming that the Fas death receptor (TNFSR6) on B cells is important for the regulation of autoimmunity since the impairment of only Fas function on B cells results in uncontrolled au...

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Detalhes bibliográficos
Main Authors: Koncz, Gabor, Hueber, Anne-Odile
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404404/
https://ncbi.nlm.nih.gov/pubmed/22848207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00207
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