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Receptor editing: an approach by autoreactive B cells to escape tolerance

To determine the fate of anti-DNA antibody-bearing B cells in normal mice, we generated transgenic mice bearing the heavy (H) and light (L) chain genes of a well-characterized anti-double-stranded DNA antibody. This antibody was originally isolated from a diseased MRL/lpr mouse and has characteristi...

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Bibliografiske detaljer
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190958/
https://ncbi.nlm.nih.gov/pubmed/8459227
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