A network of High Mobility Group box transcription factors programs innate Interleukin-17 production

How innate lymphoid cells (ILCs) in the thymus and gut become specialized effectors is unclear. The prototypic innate-like γδ T cells (Tγδ17) are a major source of interleukin-17 (IL-17). We demonstrate that Tγδ17 cells are programmed by a gene regulatory network consisting of a quartet of High Mobi...

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Main Authors: Malhotra, Nidhi, Narayan, Kavitha, Cho, Ok Hyun, Sylvia, Katelyn E., Yin, Catherine, Melichar, Heather, Rashighi, Mehdi, Lefebvre, Veronique, Harris, John E., Berg, Leslie J., Kang, Joonsoo
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811080/
https://ncbi.nlm.nih.gov/pubmed/23562159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.01.010
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