Interleukin-17 producing γδ T cells originate from SOX13(+) progenitors that are independent of γδTCR signaling

Lineage-committed αβ and γδ T cells are thought to originate from common intrathymic multipotent progenitors following instructive T cell receptor (TCR) signals. A subset of lymph node and mucosal Vγ2+ γδ T cells is progγδTCR in development of these cells remains controversial. Here we generated rep...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Spidale, Nicholas A, Sylvia, Katelyn, Narayan, Kavitha, Miu, Bing, Frascoli, Michela, Melichar, Heather J, Zhihao, Wu, Kisielow, Jan, Palin, Amy, Serwold, Thomas, Love, Paul, Kobayashi, Michihiro, Yoshimoto, Momoko, Jain, Nitya, Kang, Joonsoo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249057/
https://ncbi.nlm.nih.gov/pubmed/30413363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.09.010
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