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Threading polyintercalators with extremely slow dissociation rates and extended DNA binding sites
The development of small molecules that bind DNA sequence specifically has the potential to modulate gene expression in a general way. One mode of DNA binding is intercalation, or the insertion of molecules between DNA base pairs. We have developed a modular polyintercalation system in which interca...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3811032/ https://ncbi.nlm.nih.gov/pubmed/23919778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4057344 |
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