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The Shorter the Better: Reducing Fixed Primer Regions of Oligonucleotide Libraries for Aptamer Selection

Oligonucleotide aptamers are highly structured DNA or RNA molecules, or modified versions thereof, that can bind to targets with specific affinities comparable to antibodies. They are identified through an in vitro selection process termed SELEX (Systematic Evolution of Ligands by EXponential enrich...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pan, Weihua, Clawson, Gary A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811027/
https://ncbi.nlm.nih.gov/pubmed/19384268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14041353
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