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Primer-Free Aptamer Selection Using A Random DNA Library

Aptamers are highly structured oligonucleotides (DNA or RNA) that can bind to targets with affinities comparable to antibodies (1). They are identified through an in vitro selection process called Systematic Evolution of Ligands by EXponential enrichment (SELEX) to recognize a wide variety of target...

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Detalles Bibliográficos
Autores principales: Pan, Weihua, Xin, Ping, Patrick, Susan, Dean, Stacey, Keating, Christine, Clawson, Gary
Formato: Artigo
Lenguaje:Inglês
Publicado: MyJove Corporation 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156072/
https://ncbi.nlm.nih.gov/pubmed/20689511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2039
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