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Generation of Aptamers from A Primer-Free Randomized ssDNA Library Using Magnetic-Assisted Rapid Aptamer Selection

Aptamers are oligonucleotides that can bind to specific target molecules. Most aptamers are generated using random libraries in the standard systematic evolution of ligands by exponential enrichment (SELEX). Each random library contains oligonucleotides with a randomized central region and two fixed...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tsao, Shih-Ming, Lai, Ji-Ching, Horng, Horng-Er, Liu, Tu-Chen, Hong, Chin-Yih
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377317/
https://ncbi.nlm.nih.gov/pubmed/28367958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45478
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