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PIOGLITAZONE DOES NOT IMPROVE INSULIN SIGNALING IN MICE WITH GROWTH HORMONE OVER-EXPRESSION

Type 2 diabetes and obesity are very serious health problems in both developed and developing countries. Increased level of growth hormone (GH) is known to promote insulin resistance. Transgenic (Tg) mice over-expressing bovine GH are short-living and characterized, among others, by hyperinsulinemia...

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Bibliographic Details
Main Authors: Gesing, Adam, Bartke, Andrzej, Masternak, Michal M.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811004/
https://ncbi.nlm.nih.gov/pubmed/23946430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-13-0124
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