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Effects of Growth Hormone and Thyroxine Replacement Therapy on Insulin Signaling in Ames Dwarf Mice
Ames dwarf (Prop1(df), df/df) mice lack growth hormone (GH), prolactin, and thyrotropin and live remarkably longer than their normal siblings. Significance of reduced activity of the somatotropic and thyroid axes during development and adulthood on longevity are unknown. Because enhanced insulin sen...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844062/ https://ncbi.nlm.nih.gov/pubmed/20200088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glq018 |
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