Decreased thyroid follicle size in dwarf mice may suggest the role of growth hormone signaling in thyroid growth regulation

BACKGROUND: Altered somatotrophic signaling is among the most important potential mechanisms of extended longevity. Ames dwarf (df/df) mice are homozygous for mutation at the Prop-1 gene, leading to a lack of growth hormone (GH), prolactin and thyroid stimulating hormone (TSH). Mice homozygous for t...

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Autors principals: Gesing, Adam, Bartke, Andrzej, Masternak, Michal M, Lewiński, Andrzej, Karbownik-Lewińska, Małgorzata
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464137/
https://ncbi.nlm.nih.gov/pubmed/22897932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6614-5-7
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