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Exchange protein activated by cAMP (Epac) induces vascular relaxation by activating Ca(2+)-sensitive K(+) channels in rat mesenteric artery

Vasodilator-induced elevation of intracellular cyclic AMP (cAMP) is a central mechanism governing arterial relaxation but is incompletely understood due to the diversity of cAMP effectors. Here we investigate the role of the novel cAMP effector exchange protein directly activated by cAMP (Epac) in m...

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Bibliografische gegevens
Hoofdauteurs: Roberts, Owain Llŷr, Kamishima, Tomoko, Barrett-Jolley, Richard, Quayle, John M, Dart, Caroline
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810813/
https://ncbi.nlm.nih.gov/pubmed/23959673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.262006
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