Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca(2+)-dependent K(+) channels in cerebellar neurons

The exchange factor directly activated by cAMP (Epac) is a newly discovered direct target for cAMP and a guanine-nucleotide exchange factor for the small GTPase Rap. Little is known about the neuronal functions of Epac. Here we show that activation of Epac by specific cAMP analogs or by the pituitar...

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Detaylı Bibliyografya
Asıl Yazarlar: Ster, Jeanne, De Bock, Frédéric, Guérineau, Nathalie C., Janossy, Andrea, Barrère-Lemaire, Stéphanie, Bos, Johannes L., Bockaert, Joël, Fagni, Laurent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892910/
https://ncbi.nlm.nih.gov/pubmed/17284589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611031104
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