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Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca(2+)-dependent K(+) channels in cerebellar neurons

The exchange factor directly activated by cAMP (Epac) is a newly discovered direct target for cAMP and a guanine-nucleotide exchange factor for the small GTPase Rap. Little is known about the neuronal functions of Epac. Here we show that activation of Epac by specific cAMP analogs or by the pituitar...

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Bibliografische gegevens
Hoofdauteurs: Ster, Jeanne, De Bock, Frédéric, Guérineau, Nathalie C., Janossy, Andrea, Barrère-Lemaire, Stéphanie, Bos, Johannes L., Bockaert, Joël, Fagni, Laurent
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892910/
https://ncbi.nlm.nih.gov/pubmed/17284589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611031104
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