Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca(2+)-dependent K(+) channels in cerebellar neurons

The exchange factor directly activated by cAMP (Epac) is a newly discovered direct target for cAMP and a guanine-nucleotide exchange factor for the small GTPase Rap. Little is known about the neuronal functions of Epac. Here we show that activation of Epac by specific cAMP analogs or by the pituitar...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ster, Jeanne, De Bock, Frédéric, Guérineau, Nathalie C., Janossy, Andrea, Barrère-Lemaire, Stéphanie, Bos, Johannes L., Bockaert, Joël, Fagni, Laurent
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2007
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892910/
https://ncbi.nlm.nih.gov/pubmed/17284589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611031104
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