Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca(2+)-dependent K(+) channels in cerebellar neurons

The exchange factor directly activated by cAMP (Epac) is a newly discovered direct target for cAMP and a guanine-nucleotide exchange factor for the small GTPase Rap. Little is known about the neuronal functions of Epac. Here we show that activation of Epac by specific cAMP analogs or by the pituitar...

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Detalhes bibliográficos
Principais autores: Ster, Jeanne, De Bock, Frédéric, Guérineau, Nathalie C., Janossy, Andrea, Barrère-Lemaire, Stéphanie, Bos, Johannes L., Bockaert, Joël, Fagni, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892910/
https://ncbi.nlm.nih.gov/pubmed/17284589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611031104
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