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Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca(2+)-dependent K(+) channels in cerebellar neurons

The exchange factor directly activated by cAMP (Epac) is a newly discovered direct target for cAMP and a guanine-nucleotide exchange factor for the small GTPase Rap. Little is known about the neuronal functions of Epac. Here we show that activation of Epac by specific cAMP analogs or by the pituitar...

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書誌詳細
主要な著者: Ster, Jeanne, De Bock, Frédéric, Guérineau, Nathalie C., Janossy, Andrea, Barrère-Lemaire, Stéphanie, Bos, Johannes L., Bockaert, Joël, Fagni, Laurent
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892910/
https://ncbi.nlm.nih.gov/pubmed/17284589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611031104
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