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Induction of Leptin Resistance by Activation of cAMP-Epac Signaling

Leptin regulates energy balance and glucose homeostasis. Shortly after leptin was identified, it was established that obesity is commonly associated with leptin resistance, though the molecular mechanisms remain to be identified. To explore potential mechanisms of leptin resistance, we employed orga...

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Библиографические подробности
Главные авторы: Fukuda, Makoto, Williams, Kevin W., Gautron, Laurent, Elmquist, Joel K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747952/
https://ncbi.nlm.nih.gov/pubmed/21356522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.01.016
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