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Fatty Acids are Key in 4-Hydroxy-2-Nonenal-Mediated Activation of Uncoupling Proteins 1 and 2

The production of reactive oxygen species (ROS) in mitochondria is very sensitive to the proton motive force and may be decreased by mild uncoupling, mediated e.g. by mitochondrial uncoupling proteins (UCPs). UCPs were conversely hypothesized to be activated by ROS. Conclusions from experiments stud...

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Detalhes bibliográficos
Main Authors: Malingriaux, Elena A., Rupprecht, Anne, Gille, Lars, Jovanovic, Olga, Jezek, Petr, Jaburek, Martin, Pohl, Elena E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810126/
https://ncbi.nlm.nih.gov/pubmed/24204965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077786
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