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Inhibition of Hsp72-Mediated Protein Refolding by 4-Hydroxy-2-nonenal

A proteomic approach was applied to liver cytosol from rats fed a diet consisting of high fat and ethanol to identify 4-hydroxy-2-nonenal (4-HNE)-modified proteins in vivo. Cytosolic Hsp72, the inducible variant of the Hsp70 heat shock protein family, was consistently among the proteins modified by...

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Détails bibliographiques
Auteurs principaux: Carbone, David L., Doorn, Jonathan A., Kiebler, Zachary, Sampey, Brante P., Petersen, Dennis R.
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956495/
https://ncbi.nlm.nih.gov/pubmed/15540944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx049838g
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