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Inhibition of Hsp72-Mediated Protein Refolding by 4-Hydroxy-2-nonenal
A proteomic approach was applied to liver cytosol from rats fed a diet consisting of high fat and ethanol to identify 4-hydroxy-2-nonenal (4-HNE)-modified proteins in vivo. Cytosolic Hsp72, the inducible variant of the Hsp70 heat shock protein family, was consistently among the proteins modified by...
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Auteurs principaux: | , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2004
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956495/ https://ncbi.nlm.nih.gov/pubmed/15540944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx049838g |
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