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ATF6 modulates SREBP2-mediated lipogenesis

Activating transcription factor 6 (ATF6) and sterol regulatory element-binding proteins (SREBPs) are activated by proteolytic cleavage. The ensuing nuclear translocation of their N-termini (i.e., ATF6(N) and SREBP(N)) activates the respective target genes involved in unfolded protein response and li...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zeng, Lingfang, Lu, Min, Mori, Kazutoshi, Luo, Shengzhan, Lee, Amy S, Zhu, Yi, Shyy, John Y-J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC381012/
https://ncbi.nlm.nih.gov/pubmed/14765107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600106
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