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SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1
The synthesis of lipid and sterol species through de novo lipogenesis (DNL) is regulated by 2 functionally overlapping but distinct transcription factors: the SREBPs and carbohydrate response element–binding protein (ChREBP). ChREBP is considered to be the dominant regulator of DNL in adipose tissue...
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| Publicado en: | JCI Insight |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6693888/ https://ncbi.nlm.nih.gov/pubmed/31310592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129397 |
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