Obesity-Mediated Autophagy Insufficiency Exacerbates Proteinuria-induced Tubulointerstitial Lesions

Obesity is an independent risk factor for renal dysfunction in patients with CKDs, including diabetic nephropathy, but the mechanism underlying this connection remains unclear. Autophagy is an intracellular degradation system that maintains intracellular homeostasis by removing damaged proteins and...

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מידע ביבליוגרפי
Main Authors: Yamahara, Kosuke, Kume, Shinji, Koya, Daisuke, Tanaka, Yuki, Morita, Yoshikata, Chin-Kanasaki, Masami, Araki, Hisazumi, Isshiki, Keiji, Araki, Shin-ichi, Haneda, Masakazu, Matsusaka, Taiji, Kashiwagi, Atsunori, Maegawa, Hiroshi, Uzu, Takashi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Nephrology 2013
נושאים:
Basic Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810079/
https://ncbi.nlm.nih.gov/pubmed/24092929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012111080
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