RAF and antioxidants prevent cell death induction after growth factor abrogation through regulation of Bcl-2 proteins()

We have shown previously that mitochondrial ROS production is essential to turn growth factor (GF) removal into cell death. Activated RAF, AKT, Bcl-2 and antioxidants protected equally well against ROS accumulation and subsequent death. Here we investigated whether protection by survival signaling a...

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Hauptverfasser: Koziel, Katarzyna, Smigelskaite, Julija, Drasche, Astrid, Enthammer, Marion, Ashraf, Muhammad Imtiaz, Khalid, Sana, Troppmair, Jakob
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809515/
https://ncbi.nlm.nih.gov/pubmed/23933517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2013.07.029
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