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In vivo action of IL-27: reciprocal regulation of Th17 and Treg cells in collagen-induced arthritis

Interleukin (IL)-27 is a novel cytokine of the IL-6/IL-12 family that has been reported to be involved in the pathogenesis of autoimmune diseases and has a pivotal role as both a pro- and anti-inflammatory cytokine. We investigated the in vivo effects of IL-27 on arthritis severity in a murine colla...

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Detalhes bibliográficos
Main Authors: Moon, Su-Jin, Park, Jin-Sil, Heo, Yu-Jung, Kang, Chang-Min, Kim, Eun-Kyung, Lim, Mi-Ae, Ryu, Jun-Geol, Park, Seong Jeong, Su Park, Kyung, Sung, Young-Chul, Park, Sung-Hwan, Kim, Ho-Youn, Min, Jun-Ki, Cho, Mi-La
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809362/
https://ncbi.nlm.nih.gov/pubmed/24091748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.89
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