Interleukin-27 suppresses osteoclastogenesis via induction of interferon-γ

Interleukin (IL)-27 is a heterodimeric cytokine that is known to have both stimulatory and inhibitory functions during immune responses. We investigated the effects of IL-27 on arthritis and bone erosion in the murine collagen-induced arthritis (CIA) model. We demonstrate that the inhibitory effect...

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Autori principali: Park, Jin-Sil, Jung, Young Ok, Oh, Hye-Joa, Park, Seong Jeong, Heo, Yu-Jung, Kang, Chang-Min, Kwok, Seung-Ki, Ju, Ji Hyeon, Park, Kyung Su, Cho, Mi-La, Sung, Young-Chul, Park, Sung-Hwan, Kim, Ho-Youn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2012
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530088/
https://ncbi.nlm.nih.gov/pubmed/22812379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03622.x
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