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Molecular Mechanisms of the Biphasic Effects of Interferon-γ on Osteoclastogenesis

Although interferon-γ (IFN-γ) potently inhibits osteoclastogenesis, the suppressive effect is significantly reduced when osteoclast precursors are pre-exposed to the receptor activator of NF-κB (RANK) ligand (RANKL). However, the molecular mechanism underlying the biphasic effects of IFN-γ on osteoc...

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Detalhes bibliográficos
Main Authors: Cheng, Jing, Liu, Jianzhong, Shi, Zhenqi, Jules, Joel, Xu, Duorong, Luo, Shaokai, Wei, Shi, Feng, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255520/
https://ncbi.nlm.nih.gov/pubmed/22142221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2011.0019
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