Receptor Activator of NF-κB (RANK) Cytoplasmic IVVY(535–538) Motif Plays an Essential Role in Tumor Necrosis Factor-α (TNF)-mediated Osteoclastogenesis

Tumor necrosis factor-α (TNF) enhances osteoclast formation and activity leading to bone loss in various pathological conditions, but its precise role in osteoclastogenesis remains controversial. Although several groups showed that TNF can promote osteoclastogenesis independently of the receptor act...

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Detalhes bibliográficos
Main Authors: Jules, Joel, Shi, Zhenqi, Liu, Jianzhong, Xu, Duorong, Wang, Shunqing, Feng, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988348/
https://ncbi.nlm.nih.gov/pubmed/20870724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149484
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