The IVVY Motif and Tumor Necrosis Factor Receptor-associated Factor (TRAF) Sites in the Cytoplasmic Domain of the Receptor Activator of Nuclear Factor κB (RANK) Cooperate to Induce Osteoclastogenesis

Receptor activator of NF-κB (RANK) activation by RANK ligand (RANKL) mediates osteoclastogenesis by recruiting TNF receptor-associated factors (TRAFs) via three cytoplasmic motifs (motif 1, PFQEP(369–373); motif 2, PVQEET(559–564); and motif 3, PVQEQG(604–609)) to activate the NF-κB and MAPK signali...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jules, Joel, Wang, Shunqing, Shi, Zhenqi, Liu, Jianzhong, Wei, Shi, Feng, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583028/
https://ncbi.nlm.nih.gov/pubmed/26276390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.667535
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