Interaction of Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and Vav3 in the Receptor Activator of Nuclear Factor κB (RANK) Signaling Complex Enhances Osteoclastogenesis

The signaling pathway downstream of stimulation of receptor activator of nuclear factor κB (RANK) by RANK ligand is crucial for osteoclastogenesis. RANK recruits TNF receptor-associated factor 6 (TRAF6) to TRAF6-binding sites (T6BSs) in the RANK cytoplasmic tail (RANK(cyto)) to trigger downstream os...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yu, Jiyeon, Yun, Hyeongseok, Shin, Bongjin, Kim, Yongjin, Park, Eui-Soon, Choi, Seunga, Yu, Jungeun, Amarasekara, Dulshara Sachini, Kim, Sumi, Inoue, Jun-ichiro, Walsh, Matthew C., Choi, Yongwon, Takami, Masamichi, Rho, Jaerang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034056/
https://ncbi.nlm.nih.gov/pubmed/27507811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.728303
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