Metformin Attenuates Experimental Autoimmune Arthritis through Reciprocal Regulation of Th17/Treg Balance and Osteoclastogenesis

Metformin is widely used to suppress certain functions of the cells found in diseases including diabetes and obesity. In this study, the effects of metformin on downregulating IL-17-producing T (Th17) cells, activating and upregulating regulatory T (Treg) cells, suppressing osteoclastogenesis, and c...

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Bibliographic Details
Main Authors: Son, Hye-Jin, Lee, Jennifer, Lee, Seon-Yeong, Kim, Eun-Kyung, Park, Min-Jung, Kim, Kyoung-Woon, Park, Sung-Hwan, Cho, Mi-La
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158168/
https://ncbi.nlm.nih.gov/pubmed/25214721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/973986
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