Metformin Attenuates Experimental Autoimmune Arthritis through Reciprocal Regulation of Th17/Treg Balance and Osteoclastogenesis

Metformin is widely used to suppress certain functions of the cells found in diseases including diabetes and obesity. In this study, the effects of metformin on downregulating IL-17-producing T (Th17) cells, activating and upregulating regulatory T (Treg) cells, suppressing osteoclastogenesis, and c...

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Détails bibliographiques
Auteurs principaux: Son, Hye-Jin, Lee, Jennifer, Lee, Seon-Yeong, Kim, Eun-Kyung, Park, Min-Jung, Kim, Kyoung-Woon, Park, Sung-Hwan, Cho, Mi-La
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158168/
https://ncbi.nlm.nih.gov/pubmed/25214721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/973986
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