Metformin Attenuates Experimental Autoimmune Arthritis through Reciprocal Regulation of Th17/Treg Balance and Osteoclastogenesis

Metformin is widely used to suppress certain functions of the cells found in diseases including diabetes and obesity. In this study, the effects of metformin on downregulating IL-17-producing T (Th17) cells, activating and upregulating regulatory T (Treg) cells, suppressing osteoclastogenesis, and c...

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Bibliografski detalji
Glavni autori: Son, Hye-Jin, Lee, Jennifer, Lee, Seon-Yeong, Kim, Eun-Kyung, Park, Min-Jung, Kim, Kyoung-Woon, Park, Sung-Hwan, Cho, Mi-La
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158168/
https://ncbi.nlm.nih.gov/pubmed/25214721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/973986
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