Metformin Attenuates Experimental Autoimmune Arthritis through Reciprocal Regulation of Th17/Treg Balance and Osteoclastogenesis

Metformin is widely used to suppress certain functions of the cells found in diseases including diabetes and obesity. In this study, the effects of metformin on downregulating IL-17-producing T (Th17) cells, activating and upregulating regulatory T (Treg) cells, suppressing osteoclastogenesis, and c...

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Autors principals: Son, Hye-Jin, Lee, Jennifer, Lee, Seon-Yeong, Kim, Eun-Kyung, Park, Min-Jung, Kim, Kyoung-Woon, Park, Sung-Hwan, Cho, Mi-La
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158168/
https://ncbi.nlm.nih.gov/pubmed/25214721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/973986
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