A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases.
The covalent joining of topoisomerases to DNA is normally a transient step in the reaction cycle of these important enzymes. However, under a variety of circumstances, the covalent complex is converted to a long-lived or dead-end product that can result in chromosome breakage and cell death. We have...
Sábháilte in:
| Foilsithe in: | Proc Natl Acad Sci U S A |
|---|---|
| Príomhchruthaitheoirí: | , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
National Academy of Sciences
1996
|
| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876170/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11534 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|