A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases.

The covalent joining of topoisomerases to DNA is normally a transient step in the reaction cycle of these important enzymes. However, under a variety of circumstances, the covalent complex is converted to a long-lived or dead-end product that can result in chromosome breakage and cell death. We have...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yang, S W, Burgin, A B, Huizenga, B N, Robertson, C A, Yao, K C, Nash, H A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1996
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC38092/
https://ncbi.nlm.nih.gov/pubmed/8876170
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