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A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases.

The covalent joining of topoisomerases to DNA is normally a transient step in the reaction cycle of these important enzymes. However, under a variety of circumstances, the covalent complex is converted to a long-lived or dead-end product that can result in chromosome breakage and cell death. We have...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Yang, S W, Burgin, A B, Huizenga, B N, Robertson, C A, Yao, K C, Nash, H A
פורמט: Artigo
שפה:Inglês
יצא לאור: 1996
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC38092/
https://ncbi.nlm.nih.gov/pubmed/8876170
תגים: הוספת תג
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