A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases.
The covalent joining of topoisomerases to DNA is normally a transient step in the reaction cycle of these important enzymes. However, under a variety of circumstances, the covalent complex is converted to a long-lived or dead-end product that can result in chromosome breakage and cell death. We have...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1996
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876170/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11534 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|