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Adenylating Enzymes in Mycobacterium tuberculosis as Drug Targets

Adenylation or adenylate-forming enzymes (AEs) are widely found in nature and are responsible for the activation of carboxylic acids to intermediate acyladenylates, which are mixed anhydrides of AMP. In a second reaction, AEs catalyze the transfer of the acyl group of the acyladenylate onto a nucleo...

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Bibliografske podrobnosti
Main Authors: Duckworth, Benjamin P., Nelson, Kathryn M., Aldrich, Courtney C.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808994/
https://ncbi.nlm.nih.gov/pubmed/22283817
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