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A high-throughput screening fluorescence polarization assay for fatty acid adenylating enzymes in Mycobacterium tuberculosis

Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), encodes for an astonishing 34 fatty acid adenylating enzymes (FadDs), which play key roles in lipid metabolism. FadDs involved in lipid biosynthesis are functionally nonredundant and serve to link fatty acid and polyketide synth...

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Bibliografische gegevens
Hoofdauteurs: Grimes, Kimberly D., Aldrich, Courtney C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152590/
https://ncbi.nlm.nih.gov/pubmed/21771578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.06.037
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