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A high-throughput screening fluorescence polarization assay for fatty acid adenylating enzymes in Mycobacterium tuberculosis

Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), encodes for an astonishing 34 fatty acid adenylating enzymes (FadDs), which play key roles in lipid metabolism. FadDs involved in lipid biosynthesis are functionally nonredundant and serve to link fatty acid and polyketide synth...

詳細記述

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書誌詳細
主要な著者: Grimes, Kimberly D., Aldrich, Courtney C.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152590/
https://ncbi.nlm.nih.gov/pubmed/21771578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.06.037
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