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An experimentally-informed coarse-grained 3-site-per-nucleotide model of DNA: Structure, thermodynamics, and dynamics of hybridization

A new 3-Site-Per-Nucleotide coarse-grained model for DNA is presented. The model includes anisotropic potentials between bases involved in base stacking and base pair interactions that enable the description of relevant structural properties, including the major and minor grooves. In an improvement...

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Detalhes bibliográficos
Main Authors: Hinckley, Daniel M., Freeman, Gordon S., Whitmer, Jonathan K., de Pablo, Juan J.
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808442/
https://ncbi.nlm.nih.gov/pubmed/24116642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4822042
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