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Solvation free energies and partition coefficients with the coarse-grained and hybrid all-atom/coarse-grained MARTINI models

We present the estimation of solvation free energies of small solutes in water, n-octanol and hexane using molecular dynamics simulations with two MARTINI models at different resolutions, viz. the coarse-grained (CG) and the hybrid all-atom/coarse-grained (AA/CG) models. From these estimates, we als...

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Detalhes bibliográficos
Publicado no:J Comput Aided Mol Des
Autor principal: Genheden, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649594/
https://ncbi.nlm.nih.gov/pubmed/28875361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-017-0059-9
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