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Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases
The Rho/rho-kinase (ROCK) pathway has an important role in the pathogenesis of several cardiovascular diseases. The activation of ROCK is involved in the regulation of vascular tone, endothelial dysfunction, inflammation and remodeling. The inhibition of ROCK has a beneficial effect in a variety of...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3807099/ https://ncbi.nlm.nih.gov/pubmed/20601092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2010.06.011 |
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