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Rho kinase as a therapeutic target in cardiovascular disease
Rho kinase (ROCK) belongs to the AGC (PKA/PKG/PKC) family of serine/threonine kinases and is a major downstream effector of the small GTPase RhoA. ROCK plays central roles in the organization of the actin cytoskeleton and is involved in a wide range of fundamental cellular functions such as contract...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193795/ https://ncbi.nlm.nih.gov/pubmed/21929346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fca.11.51 |
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