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Rho kinase as a therapeutic target in cardiovascular disease

Rho kinase (ROCK) belongs to the AGC (PKA/PKG/PKC) family of serine/threonine kinases and is a major downstream effector of the small GTPase RhoA. ROCK plays central roles in the organization of the actin cytoskeleton and is involved in a wide range of fundamental cellular functions such as contract...

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書目詳細資料
Main Authors: Surma, Michelle, Wei, Lei, Shi, Jianjian
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193795/
https://ncbi.nlm.nih.gov/pubmed/21929346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fca.11.51
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