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Rolipram Improves Renal Perfusion and Function during Sepsis in the Mouse
Microcirculatory dysfunction is correlated with increased mortality among septic patients and is believed to be a major contributor to the development of acute kidney injury (AKI). Rolipram, a selective phosphodiesterase 4 (PDE4) inhibitor, has been shown to reduce microvascular permeability and in...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3807062/ https://ncbi.nlm.nih.gov/pubmed/24018639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.208520 |
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