Development of Oxidative Stress in the Peritubular Capillary Microenvironment Mediates Sepsis-Induced Renal Microcirculatory Failure and Acute Kidney Injury

Acute kidney injury is a frequent and serious complication of sepsis. To better understand the development of sepsis-induced acute kidney injury, we performed the first time-dependent studies to document changes in renal hemodynamics and oxidant generation in the peritubular microenvironment using t...

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Detalles Bibliográficos
Main Authors: Wang, Zhen, Holthoff, Joseph H., Seely, Kathryn A., Pathak, Elina, Spencer, Horace J., Gokden, Neriman, Mayeux, Philip R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349842/
https://ncbi.nlm.nih.gov/pubmed/22119717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.10.011
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