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Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury

The mortality rate of patients who develop acute kidney injury during sepsis nearly doubles. The effectiveness of therapy is hampered because it is usually initiated only after the onset of symptoms. As renal microvascular failure during sepsis is correlated with the generation of reactive nitrogen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Holthoff, Joseph H., Wang, Zhen, Seely, Kathryn A., Gokden, Neriman, Mayeux, Philip R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326404/
https://ncbi.nlm.nih.gov/pubmed/21975863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.347
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