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Mitochondrial Alterations near Amyloid Plaques in an Alzheimer's Disease Mouse Model

While accumulation of amyloid-β (Aβ) deposited as senile plaques is a hallmark feature of Alzheimer's disease (AD), the neurotoxicity of these deposits remains controversial. Recent in vitro studies suggested a link between elevated Aβ and mitochondrial dysfunction that might contribute to the...

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Detalhes bibliográficos
Main Authors: Xie, Hong, Guan, JiSong, Borrelli, Laura A., Xu, Jing, Serrano-Pozo, Alberto, Bacskai, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807029/
https://ncbi.nlm.nih.gov/pubmed/24155308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1836-13.2013
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