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Label-free imaging of amyloid plaques in Alzheimer’s disease with stimulated Raman scattering microscopy
One of the key pathological features of Alzheimer’s disease (AD) is the existence of extracellular deposition of amyloid plaques formed with misfolded amyloid-β (Aβ). The conformational change of proteins leads to enriched contents of β sheets, resulting in remarkable changes of vibrational spectra,...
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| Publicado no: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6239428/ https://ncbi.nlm.nih.gov/pubmed/30456301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat7715 |
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