Загрузка...

Treatment of Niemann–Pick Type C Disease by Histone Deacetylase Inhibitors

Niemann–Pick type C disease (NPC) is a devastating, recessive, inherited disorder that causes accumulation of cholesterol and other lipids in late endosomes and lysosomes. Mutations in 2 genes, NPC1 and NPC2, are responsible for the disease, which affects about 1 in 120,000 live births. About 95 % o...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Helquist, Paul, Maxfield, Frederick R., Wiech, Norbert L., Wiest, Olaf
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805865/
https://ncbi.nlm.nih.gov/pubmed/24048860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0217-2
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!