Two Replication Fork Maintenance Pathways Fuse Inverted Repeats to Rearrange Chromosomes

Replication fork (RF) maintenance pathways preserve chromosomes, but their faulty application at nonallelic repeats could generate rearrangements causing cancer, genomic disorders and speciation(1-3). Potential causal mechanisms are homologous recombination (HR) and error-free postreplication repair...

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Autors principals: Hu, Lingchuan, Kim, Tae Moon, Son, Mi Young, Kim, Sung-A, Holland, Cory L., Tateishi, Satoshi, Kim, Dong Hyun, Yew, P. Renee, Montagna, Cristina, Dumitrache, Lavinia C., Hasty, Paul
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805358/
https://ncbi.nlm.nih.gov/pubmed/24013173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12500
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