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DAP12 Promotes IRAK-M Expression and IL-10 Production by Liver Myeloid Dendritic Cells and Restrains Their T Cell Allostimulatory Ability()
Freshly-isolated hepatic dendritic cells (DC) are comparatively immature, relatively resistant to maturation, and can down-modulate effector T cell responses. Molecular mechanisms that underlie these properties are ill-defined. DNAX-activating protein of 12 kDa (DAP12) is an ITAM-bearing transmembra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805281/ https://ncbi.nlm.nih.gov/pubmed/21257958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000527 |
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